Stroke in Myopathies

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Stroke in myopathies.

OBJECTIVES Only few data are available about the risk of myopathy patients experiencing a cerebral stroke. AIMS To review the current knowledge about the frequency, pathogenesis, and outcome of stroke in primary/secondary myopathies. METHODS Literature review of all human studies dealing with stroke in primary/secondary myopathies. RESULTS Stroke in myopathies may be either ischemic, meta...

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Congenital myopathies.

This review focuses on congenital myopathies, a distinct but markedly heterogeneous group of muscle disorders that present with muscle weakness and typically appear at birth or in infancy. These myopathies have characteristic histopathologic abnormalities on muscle biopsy, allowing a preliminary morphologic classification. Advances in molecular genetics have allowed a more rational classificati...

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Metabolic myopathies.

PURPOSE OF REVIEW The metabolic myopathies result from inborn errors of metabolism affecting intracellular energy production due to defects in glycogen, lipid, adenine nucleotides, and mitochondrial metabolism. This article provides an overview of the most common metabolic myopathies. RECENT FINDINGS Our knowledge of metabolic myopathies has expanded rapidly in recent years, providing us with...

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Toxic myopathies.

PURPOSE This article reviews the most important muscle toxins, many of which are widely prescribed medications. Particular emphasis is placed on statins, which cause muscle symptoms in a relatively large proportion of the patients who take them. RECENT FINDINGS As with other toxic myopathies, most cases of statin-associated myotoxicity are self-limited and subside with discontinuation of the ...

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Distal myopathies.

Although muscle disease classically presents with proximal extremity weakness, some myopathic disorders, including several types of muscular dystrophy, result in predominantly, or exclusively, distal muscle involvement. Accurate diagnosis of these relatively uncommon conditions can be challenging for the clinician, because of both the unusual phenotype and the significant overlap in the clinica...

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ژورنال

عنوان ژورنال: Cerebrovascular Diseases

سال: 2010

ISSN: 1421-9786,1015-9770

DOI: 10.1159/000255968